Transcriptomic profiling of human γδ T cells reveals non-linear immune aging characterized by childhood transitions and relative stability in adulthood
Tao Yang, Ximena León-Lara, Vicente Almeida, Ziqing Wang, Yusuf Eshimutu Abu, Anika Janssen, Charlotte Kleine-wechelmann, Ahmed Hassan, Zheng Song, Moana Dempsey, Likai Tan, Martin Boehne, Constantin von Kaisenberg, Immo Prinz, Reinhold Förster, Sarina Ravens
This study maps the aging trajectories of human γδ T cells using single-cell transcriptomics, revealing non-linear aging with distinct childhood transitions and stability in adulthood.
bioRxiv · Jan 16, 2026 · PreprintImmunology