Bruno Cavadas

The paper conducts a GWAS in the Portuguese population to identify migraine risk loci, finding a novel association with the NPS gene and highlighting potential therapeutic targets.

This study shows MEX3A regulates PPARγ expression in colorectal cancer, affecting tumor growth and chemotherapy response.

The paper identifies phosphorylation of membrane trafficking regulators, particularly SEC16A, as key to FER-mediated invasion in TNBC organoids.

This study shows that meningeal γδ17 T cells promote bacterial entry into the brain during neonatal meningitis and cause long-term behavioral issues.

This study uses patient-derived organoids to analyze glycosylation changes in gastric tissues and shows they mimic in vivo glycosylation profiles and H. pylori interactions.

The paper models ancestry in Arabians and Iranians, finding strong west-east population structure and evidence linking east Arabians to basal Eurasians.

The paper introduces IPCAPS, an unsupervised clustering method using iterative pruning to detect fine-scale population structure from SNP data, showing improved accuracy over existing tools in simulations.