Meningeal γδ T cells facilitate bacterial entry into the brain in neonatal meningitis and trigger long-term behavioural sequelae
Inês Lorga, Joana Soares, Joana Bravo, Pedro Mesquita, Nuno Ribeiro, João Rodrigues, Ahmed Hassan, Morgana Mesquita, Bruno Cavadas, Hristo Georgiev, Ana Magalhães, Teresa Summavielle, Manuel Vilanova, Julie C. Ribot, Elva Bonifácio Andrade
This study shows that meningeal γδ17 T cells promote bacterial entry into the brain during neonatal meningitis and cause long-term behavioral issues.
bioRxiv · Nov 7, 2025 · PreprintImmunology