Author

Shuhua Fu

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2 Genomics· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 5 Organism:mouse· 5 Research Focus:differential expression· 4 Approach:statistical model· 4 Assay:DNA methylation· 3 Research Focus:gene regulatory network inference· 3 Assay:ChIP-seq· 2 Research Focus:database / resource· 2

Frequent Co-Authors

Bo ZhangiD· 5 shared Benpeng MiaoiD· 4 shared Marisa S. BartolomeiiD· 4 shared Ting WangiD· 4 shared Cheryl Walker· 3 shared Cristian CoarfaiD· 3 shared Daofeng LiiD· 3 shared Prashant Kumar KuntalaiD· 3 shared

Activity by Year

2025-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersGenomics

Bo ZhangORCID

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Author profile →

5 papers

Recent·Most cited

Lifecourse sex-specific molecular response to early-life exposures of toxic substances

Shuhua Fu, Benpeng Miao, Wanqing Shao, Cristian Coarfa, Ravindra Kumar, Prashant Kumar Kuntala, Bongsoo Park, Sandra L. Grimm, Rahul Kumar Jangid, Justin A. Colacino, Xiaoyun Xing, Daofeng Li, Shaopeng Liu, Robert B. Hamanaka, Claudia Lalancette, , Bo Zhang

The paper investigates sex-specific molecular responses to early-life toxicant exposures in mice across multiple life stages using transcriptomic and epigenomic data.

bioRxiv · Aug 25, 2026 · PreprintGenomics

Comprehensive Transcriptomic and Epigenomic Insights into Environmental Toxicant Exposures: The TaRGET II Resource

Bo Zhang, Benpeng Miao, Shuhua Fu, Cristian Coarfa, Ravindra Kumar, Prashant Kumar Kuntala, Bongsoo Park, Sandra L. Grimm, Rahul Kumar Jangid, Justin A. Colacino, Laurie K. Svoboda, Wanqing Shao, Xiaoyun Xing, Daofeng Li, Shaopeng Liu, , Cheryl Walker

The paper characterizes persistent epigenomic and transcriptomic changes in mice exposed to environmental toxicants across life stages, revealing widespread gene expression and chromatin alterations.

bioRxiv · Jul 28, 2025 · PreprintPharmacology & Toxicology

ToxiTaRGET: a multi-omics resource for toxicant-responsive molecular targets

Ravindra Kumar, Tianyi Fu, Prashant Kumar Kuntala, Benpeng Miao, Shuhua Fu, Daofeng Li, Marisa S. Bartolomei, Cheryl Walker, Ting Wang, Bo Zhang

ToxiTaRGET provides a multi-omics resource of molecular responses to toxicants in mice, enabling researchers to explore transcriptomic and epigenomic changes across tissues and life stages.

bioRxiv · Jul 28, 2025 · PreprintBioinformatics

The impact of environmental exposures on the epigenomic and transcriptomic landscape of transposable elements

Benpeng Miao, Yu Zhang, Wanqing Shao, Shuhua Fu, Marisa S. Bartolomei, Cheryl Walker, Cristian Coarfa, Bo Zhang, Ting Wang

This study examines how early-life exposure to environmental toxicants alters TE chromatin accessibility and expression in mouse liver, revealing exposure-specific and sex-dependent effects.

bioRxiv · Jul 28, 2025 · PreprintGenomics

Quantification of single cell-type-specific alternative transcript initiation

Shuhua Fu, Parker C. Wilson, Bo Zhang

The paper introduces TSRdetector, a method to analyze differential usage of gene transcription start regions across tissues, cell types, and diseases, revealing unique transcriptional regulation patterns.

bioRxiv · Apr 29, 2025 · PreprintBioinformatics