Carson J. Purnell

The paper trains segmentation networks for cryo-ET data using synthetic and real data, showing that synthetic data with molecular diversity improves performance but real data is needed for generalization.

This study uses cryo-ET to reveal novel chromatin folding motifs in native human chromatin and shows how histone citrullination affects nucleosome stacking and self-association.

This study identifies FDG hyper-metabolism in cerebellar and olfactory regions in Alzheimer's disease, suggesting disrupted inhibitory networks.