Compromised 2-start zigzag chromatin folding in immature mouse retina cells driven by irregularly spaced nucleosomes with short DNA linkers.
Brianna Kable, Stephanie Portillo‐Ledesma, Evgenya Y. Popova, Nathan Jentink, Matthew T. Swulius, Zilong Li, Tamar Schlick A, Sergei A. Grigoryev
The paper investigates chromatin structure in immature and mature mouse retina cells, finding that short DNA linkers disrupt the two-start zigzag folding, leading to less compact chromatin in immature cells.
Nucleic Acids Research · May 22, 2025Peer-reviewedMolecular Biology