M. Neal Waxham

This study compares the structural and mechanical properties of actin bundles formed by CaMKII with those formed by canonical cross-linkers, revealing unique flexibility and curvature in CaMKII bundles.

This study identifies PP2A and CDK16 as regulators of WIPI2B phosphorylation and neuronal autophagosome biogenesis, showing their antagonistic roles in this process.

The paper uses cryo-electron tomography to study axonal organelle organization, revealing how spatial confinement influences membrane remodeling and organelle morphology.

This study investigates how chain length mismatch and acyl chain position affect lateral organization in high-melting lipids, showing strong correlations between phase behavior and saturated lipid melting temperature.

The paper shows that wild-type cortical neurons form and extrude calcium-phosphate sheets associated with mitochondria, suggesting a role in pathological calcification in neurological disorders.

The paper uses cryo-ET and a Surface Morphometrics pipeline to measure membrane thickness in organellar subcompartments, revealing variations and correlations with structural features.

The paper trains segmentation networks for cryo-ET data using synthetic and real data, showing that synthetic data with molecular diversity improves performance but real data is needed for generalization.

This study investigates how halogenated cholesterol affects lipid phase behavior in ternary membranes using cryo-EM and fluorescence microscopy.

The paper identifies a Pdlim5:PalmD protein complex that regulates dendrite branching in rat hippocampal neurons through functional interdependence.

This study uses cryo-electron tomography to show that spatial restrictions in axons and presynaptic varicosities influence mitochondrial morphology and membrane organization.