Frederick A. Heberle

This study shows that nanoscale lipid clustering enhances influenza viral binding by increasing local glycosphingolipid concentration, with binding avidity dependent on the spatiotemporal scales of this clustering.

This study quantifies interleaflet coupling in asymmetric lipid bilayers and observes anti-registered phases in 14:1-PC systems.

This study investigates how chain length mismatch and acyl chain position affect lateral organization in high-melting lipids, showing strong correlations between phase behavior and saturated lipid melting temperature.

The paper develops a method to quantify the nanoscopic miscibility transition temperature in lipid bilayers using FRET measurements and validates it with simulations.

The paper uses cryo-ET and a Surface Morphometrics pipeline to measure membrane thickness in organellar subcompartments, revealing variations and correlations with structural features.

The paper introduces three new methods to quantify dynamic interdigitation in lipid bilayers using atomistic simulations, providing detailed insights into interleaflet interactions.

The paper trains segmentation networks for cryo-ET data using synthetic and real data, showing that synthetic data with molecular diversity improves performance but real data is needed for generalization.

This study investigates how halogenated cholesterol affects lipid phase behavior in ternary membranes using cryo-EM and fluorescence microscopy.

The paper uses calcium-induced hemifusion to create asymmetric GUVs and studies phase behavior changes, finding variability in outer leaflet exchange and correlation with asymmetry.