Author

Charlotte Avanzi

École Polytechnique Fédérale de LausanneORCID 0000-0002-1062-4058Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexandra AubryiD· 1 shared Alexandre GodmeriD· 1 shared Andrej BenjakiD· 1 shared Aurélie ChauffouriD· 1 shared Bettina Broeckling· 1 shared Corentin PoignoniD· 1 shared Emmanuelle CambauiD· 1 shared Euzenir Nunes SarnoiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

Alexandra AubryORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJun 5, 2026

Minimal effective dose of telacebec administered orally in a murine model of leprosy

Aurélie Chauffour, Charlotte Avanzi, Alexandre Godmer…·Alexandra Aubry

This study determines the minimal effective oral dose of telacebec against M. leprae in a mouse model, finding 20 mg/kg achieves complete bacterial clearance.

DOI 10.64898/2026.06.05.730402

mousebulk RNA-seq

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Molecular BiologyPLoS PathogensPeer-reviewedOct 25, 2021

A new paradigm for leprosy diagnosis based on host gene expression

Thyago Leal-Calvo, Charlotte Avanzi, Mayara Abud Mendes…·Milton Ozório Moraes

This study identifies gene expression biomarkers to distinguish leprosy subtypes from other skin conditions using bulk RNA-sequencing.

20 citations

humanbulk RNA-seq

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