Author

Margaret Gatz

University of Southern CaliforniaORCID 0000-0002-1071-9970Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2

Signature Assays, Organisms & Methods

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Assay:GWAS summary statistics· 2 Organism:human· 2 Research Focus:polygenic risk· 2 Approach:statistical model· 2

Frequent Co-Authors

Anbupalam ThalamuthuiD· 2 shared Ida KarlssoniD· 2 shared Karen A. MatheriD· 2 shared Nancy L. PederseniD· 2 shared Alexey A. ShadriniD· 1 shared Benjamin Grenier‐BoleyiD· 1 shared Chandra A. ReynoldsiD· 1 shared Christine Fennema‐NotestineiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Anbupalam ThalamuthuORCID

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Author profile →

2 papers

Recent·Most cited

Evaluating a Genome-Wide Polygenic Score for Handgrip Strength and Its Interplay with Leisure-Time Physical Activity Across the IGEMS Twin Cohorts

Päivi Herranen, Teemu Palviainen, Marianne Nygaard, Ida Karlsson, Anbupalam Thalamuthu, Karen A. Mather, Chandra A. Reynolds, Matthew S. Panizzon, Taina Rantanen, Deborah Finkel, Margaret Gatz, Nancy L. Pedersen, Jaakko A. Kaprio, Elina Sillanpää

The paper evaluates a polygenic score for handgrip strength and its interaction with physical activity across twin cohorts, finding a significant genetic association and effect modification by physical activity.

Medicine & Science in Sports & Exercise · Apr 28, 2026Peer-reviewedGenetic & Genomic Medicine

Polygenic resilience scores capture protective genetic effects for Alzheimers disease

Jiahui Hou, Jonathan Hess, Nicola J. Armstrong, Joshua C. Bis, Benjamin Grenier‐Boley, Ida Karlsson, Ganna Leonenko, Katya T. Numbers, Eleanor K. O’Brien, Alexey A. Shadrin, Anbupalam Thalamuthu, Qiong Yang, Ole A. Andreassen, Henry Brodaty, Margaret Gatz, , Stephen J. Glatt

This study identifies genetic resilience factors for Alzheimer's disease by constructing polygenic resilience scores that reduce genetic risk penetrance and correlate with polygenic risk scores in unaffected individuals.

Translational Psychiatry · Jul 25, 2022Peer-reviewedGenetic & Genomic Medicine