Ida Karlsson

The paper evaluates a polygenic score for handgrip strength and its interaction with physical activity across twin cohorts, finding a significant genetic association and effect modification by physical activity.

This study identifies 118 new genetic loci associated with Alzheimer's disease across diverse ancestries and discovers 48 novel risk loci, including those enriched in neuronal cell types.

This study identifies genetic resilience factors for Alzheimer's disease by constructing polygenic resilience scores that reduce genetic risk penetrance and correlate with polygenic risk scores in unaffected individuals.

This study identifies seven novel genetic loci for Alzheimer's disease using a large GWAS and highlights microglia and immune pathways as key contributors to disease pathology.

This study examines the accumulation of epigenetic mutations with age using longitudinal blood samples and identifies factors influencing their occurrence.

The paper identifies DNA methylation differences in peripheral blood of Alzheimer’s disease discordant twin pairs, linking these to brain gene expression and neuronal functions.

This study identifies 206 new genomic loci and 1,041 genes associated with intelligence using a large GWAS meta-analysis of 279,930 individuals.

This study identifies 99 genetic loci associated with general cognitive function using data from 280,360 individuals, finding genes linked to brain structure and neurodegenerative disorders.

This study identifies 9 novel genetic loci and 215 potential causative genes associated with Alzheimer's disease risk through a large genome-wide association analysis.