Daniël Roelfs

Genetic overlap between multivariate measures of human functional brain connectivity and psychiatric disorders

This study identifies genetic overlap between functional brain connectivity and six psychiatric disorders using multivariate genome-wide association analysis in 30,701 UK Biobank individuals.

Abundant pleiotropy across neuroimaging modalities identified through a multivariate genome-wide association study

The paper identifies abundant genetic pleiotropy across neuroimaging modalities using a multivariate genome-wide association study in two cohorts.

Shared genetic architecture between mental health and the brain functional connectome in the UK Biobank

The paper identifies shared genetic variants between self-reported mental health and brain functional connectivity in the UK Biobank using multivariate statistical methods.

Evidence for widespread alterations in cortical microstructure after 32 hours of sleep deprivation

This study shows that 32 hours of sleep deprivation increases the T1w/T2w ratio in specific cortical regions compared to a normal sleep-wake cycle.

The genetic architecture of human cortical folding

This study identifies 856 genetic loci associated with sulcal depth through a genome-wide association study using UK Biobank data, showing higher heritability and locus yield compared to cortical thickness and surface area.

Evidence for reduced long-term potentiation-like visual cortical plasticity in schizophrenia and bipolar disorder

The paper assesses LTP-like visual cortical plasticity in schizophrenia and bipolar disorder using VEP modulation, finding impaired N1b modulation in SZ and BDI but not BDII, linked to symptom severity.

Sleep and sleep deprivation differentially alter white matter microstructure: a mixed model design utilising advanced diffusion modelling

This study uses mixed models and advanced diffusion imaging to show that sleep deprivation and normal sleep-wake cycles differentially affect white matter microstructure.

Experience-dependent modulation of the visual evoked potential: testing effect sizes, retention over time, and associations with age in 415 healthy individuals

The paper examines VEP modulation in 415 healthy individuals, finding significant effects for several components and age-related correlations, supporting VEP as a measure of synaptic plasticity.