Vulnerability to memory decline in aging. A mega-analysis of structural brain change.
Dídac Vidal-piñeiro A, Øystein Sørensen, Marie Strømstad, Inge K. Amlien, William F.C. Baaré, David Bartrés-faz A, Andreas M. Brandmaier, Gabriele Cattaneo, Sandra Düzel, Paolo Ghisletta, Richard N. Henson, Simone Kühn, Ulman Lindenberger, Athanasia M. Mowinckel, Lars H Nyberg, , Anders M. Fjell
This study investigates the relationship between brain atrophy and memory decline in aging using longitudinal data, finding a nonlinear association that intensifies with age and is influenced by APOE ε4 carriership.
bioRxiv · Mar 27, 2025 · PreprintNeuroscience