Human Cells for Human Proteins: Isotope Labeling in Mammalian Cells for Functional NMR Studies of Disease-Relevant Proteins
Philip Rößler, M. Ruckstuhl, Arnelle Löbbert, Timo T. Stühlinger, Lucia Rosanna Franchini, Ching‐Ju Tsai, Roman J. Lichtenecker, Binesh Shrestha, Simon Rüdisser, Robert Konrat, Gebhard F. X. Schertler, Alvar D. Gossert
The paper develops cost-effective isotope labeling protocols in HEK293 cells for NMR studies of difficult-to-produce human proteins, enabling detailed structural and functional analysis.
Protein Science · Mar 9, 2026Peer-reviewedBiophysics