Author

Jeffrey M. Malgady

Stony Brook UniversityORCID 0000-0002-1129-2155Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Joshua L. PlotkiniD· 3 shared Joshua A. GoldbergiD· 2 shared Lior MatityahuiD· 2 shared Zachary B. HobeliD· 2 shared Alexander Baez· 1 shared Eric M. PrageriD· 1 shared Gilad SilberbergiD· 1 shared Guoping FengiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersNeuroscience

Joshua L. PlotkinORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Synchronous activation of striatal cholinergic interneurons induces local serotonin release

Lior Matityahu, Zachary B. Hobel, Noa Berkowitz, Jeffrey M. Malgady, Naomi Gilin, Joshua L. Plotkin, Joshua A. Goldberg

The paper shows that synchronous activation of striatal cholinergic interneurons induces local serotonin release through a mechanism similar to dopamine release.

Nature Communications · Mar 16, 2026Peer-reviewedNeuroscience

A tonic nicotinic brake controls spike timing in striatal spiny projection neurons

Lior Matityahu, Jeffrey M. Malgady, Meital Schirelman, Yvonne Johansson, Jennifer A. Wilking, Gilad Silberberg, Joshua A. Goldberg, Joshua L. Plotkin

This study shows that tonic activation of 4β2 nicotinic acetylcholine receptors on GABAergic interneurons primes feedforward inhibition, shaping striatal output timing and synaptic plasticity.

eLife · May 17, 2022Peer-reviewedNeuroscience

Non-synaptic alterations in striatal excitability and cholinergic modulation in a SAPAP3 mouse model of compulsive motor behavior

Jeffrey M. Malgady, Alexander Baez, Kimberly Jimenez, Zachary B. Hobel, Eric M. Prager, Qiangge Zhang, Guoping Feng, Joshua L. Plotkin

This study investigates how SAPAP3 deletion affects striatal circuit function in a mouse model of compulsive motor behavior, revealing non-synaptic and pathway-specific changes.

bioRxiv · Feb 7, 2022 · PreprintNeuroscience