Qiangge Zhang

The paper identifies sibling-derived chimerism in microglia and macrophages across marmoset tissues using single-cell RNA-seq, showing hematopoietic origin and regional variation in brain microglia.

This paper creates a cross-species spatial transcriptomic atlas of the basal ganglia in human, rhesus macaque, and common marmoset, revealing conserved molecular organization and cell type-specific compartments.

The paper presents a spatially resolved transcriptomic and gene regulatory atlas of primate subcortical regions, revealing spatially tuned transcriptional and regulatory programs across cell types.

The paper investigates how astrocyte regional specialization develops in mouse and marmoset brains using single-nucleus RNA sequencing and expansion microscopy, finding significant regional and developmental changes in gene expression and morphology.

This study profiles marmoset foveal and peripheral retinal cells across development, revealing conserved cell types and distinct molecular maturation paths.

The paper analyzes single-nucleus RNA sequencing data from marmoset brain cells to show that neuronal identity is more influenced by developmental origin than functional class.

The paper introduces SPIN, a method to mitigate autocorrelation in spatial transcriptomics by subsampling neighbors, improving existing methods and enabling joint analysis across datasets.

The paper analyzes gene regulatory programs in the neocortex of rodents and primates using single-cell multiomics, finding rapid evolution of cell type-specific gene expression and TE-driven cCREs.

This study shows that deleting GIT1 in the brain impairs cognition and disrupts phosphorylation networks of synaptic proteins linked to schizophrenia and neurodevelopmental disorders.

This study investigates how SAPAP3 deletion affects striatal circuit function in a mouse model of compulsive motor behavior, revealing non-synaptic and pathway-specific changes.

The paper profiles interneurons in primates and rodents to identify evolutionary innovations in brain cell types and their molecular features.

The paper identifies enhancers for targeting specific neuronal subtypes across species and demonstrates their utility in circuit manipulation.

This study demonstrates that RAD51 enhances interhomolog repair in zygotes, enabling efficient homozygous knock-in without exogenous templates.