GenomicsbioRxivPreprint
Structure-function analysis of PI3K signalling cascade base editing screens in cancer cells
Katrina McCarten, Barbara Abreu, Benoît Baillif…·Mathew J. Garnett
The paper uses CRISPR base editing and structural analysis to identify functional residues in the PI3K pathway, revealing potential drug targets and allosteric pockets.
DOI 10.64898/2026.09.08.748517