Author

Barbara Abreu

University of Warwick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Alex Watterson· 1 shared Alexander StevensiD· 1 shared Benoît BaillifiD· 1 shared Cansu DinçeriD· 1 shared David A. BakeriD· 1 shared Emre KarakoçiD· 1 shared Erik G. MarklundiD· 1 shared Gabriele PiccoiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Alex Watterson

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Structure-function analysis of PI3K signalling cascade base editing screens in cancer cells

Katrina McCarten, Barbara Abreu, Benoît Baillif, Lisa Koob, Jong Sook Ahn, Cansu Dinçer, Julian Esselborn, Emre Karakoç, R. Frederick Ludlow, John F. Lyons, Gabriele Picco, Mamta Sharma, Marcel L. Verdonk, Mark R. Wade, Samantha J. Walker, , Mathew J. Garnett

The paper uses CRISPR base editing and structural analysis to identify functional residues in the PI3K pathway, revealing potential drug targets and allosteric pockets.

bioRxiv · Sep 14, 2026 · PreprintGenomics

Native mass spectrometry of membrane protein lipid and ligand complexes using de novo designed WRAP domains

Surabhi Kokane, Ljubica Mihaljević, Barbara Abreu, Stijn de Schepper, Alexander Stevens, Erik G. Marklund, David A. Baker, Phillip J. Stansfeld, Michael Landreh

The paper demonstrates that WRAP domains designed with deep learning can preserve weak interactions of membrane protein complexes in native mass spectrometry, enabling characterization of lipid and ligand interactions without detergent micelles.

bioRxiv · Jul 25, 2026 · PreprintBiophysics