Author

Gwendolyn M. Cramer

The Wistar InstituteORCID 0000-0002-1141-3391Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Adi Narayana Reddy PoliiD· 1 shared Andrew V. KossenkoviD· 1 shared Avishek BhuniyaiD· 1 shared Bryan BristowiD· 1 shared Colin HartiD· 1 shared David B. WeineriD· 1 shared Dmitry I. ZhigareviD· 1 shared Eric Struth· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

Adi Narayana Reddy PoliORCID

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2 papers

Recent·Most cited

Targeting LxCxE cleft pocket of retinoblastoma protein in M2 macrophages inhibits ovarian cancer progression

Evgenii N. Tcyganov, Taekyoung Kwak, Xue Yang, Adi Narayana Reddy Poli, Colin Hart, Avishek Bhuniya, Joel A. Cassel, Andrew V. Kossenkov, Noam Auslander, Lily Sia Lu, Paridhima Sharma, Maria De Grecia Cauti Mendoza, Dmitry I. Zhigarev, Gwendolyn M. Cramer, Mark Gregory Cadungog, , Luis J. Montaner

This study shows targeting the LxCxE cleft pocket of Rb in M2 macrophages inhibits ovarian cancer progression by reducing immunosuppressive TAMs and enhancing T cell infiltration.

Cancer Immunology Research · Sep 9, 2025Peer-reviewedImmunology

Drug resistant pancreatic cancer cells exhibit altered biophysical interactions with stromal fibroblasts in imaging studies of 3D co-culture models

Eric Struth, Maryam Labaf, Vida Karimnia, Yiran Liu, Gwendolyn M. Cramer, Joanna B. Dahl, Frank John Slack, Kourosh Zarringhalam, Jonathan P. Celli

This study investigates how drug-resistant pancreatic cancer cells alter biophysical interactions with stromal fibroblasts in 3D co-culture models using imaging and RNA-seq analysis.

Scientific Reports · Sep 5, 2024Peer-reviewedBiophysics