Author

Zhen Luo

Jinan UniversityORCID 0000-0002-1142-2845Unclaimed ORCID profile · follow to get notified of new preprints

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Zhen Luo2 papers · Washington University in St. Louis

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Jiuxiu Lin· 1 shared Menglan Rao· 1 shared Shuang Liu· 1 shared Yicong Liang· 1 shared Yue KongiD· 1 shared Zhiwei LeiiD· 1 shared Zicong Chen· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Jiuxiu Lin

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1 paper

Recent·Most cited

MicrobiologyJournal of VirologyPeer-reviewedApr 27, 2026

PTBP1 is upregulated by Zika virus infection via HIF-1alpha signal and hijacks NS1 protein to induce NS1 degradation to restrain viral replication

Menglan Rao, Yue Kong, Shuang Liu…·Zhen Luo

This study identifies that ZIKV upregulates PTBP1 via HIF-1alpha, which then binds NS1 to promote its degradation, thereby inhibiting viral replication.

DOI 10.1128/jvi.01495-25

humanexperimental assay

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