Peng Yao

This study shows that inactivating a uORF in the Gata4 gene in mice leads to increased GATA4 translation and cardiac hypertrophy.

This study shows that FAK and p130Cas modulate early transcription and metabolism in response to substrate stiffness using RNA sequencing in mouse cells.

The paper identifies dsRNA structures in uORFs that regulate translation and shows ASO targeting can modulate mORF translation and reduce cardiac hypertrophy.

This study identifies PRRC2B as an RNA binding protein that regulates translation of specific mRNAs, including cell cycle regulators, and inhibits cell proliferation by affecting G1/S phase transition.