Author

Eng-Soon Khor

University of Rochester MedicineORCID 0000-0003-3109-8293Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:multiome· 1

Frequent Co-Authors

Feng JiangiD· 2 shared Jiangbin WuiD· 2 shared Omar M. HedayaiD· 2 shared Peng YaoiD· 2 shared Christoph PröscheliD· 1 shared David H. MathewsiD· 1 shared Kadiam C. Venkata SubbaiahiD· 1 shared Li Huitong XieiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersMolecular Biology

Feng JiangORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedOct 3, 2023

Secondary structures that regulate mRNA translation provide insights for ASO-mediated modulation of cardiac hypertrophy

Omar M. Hedaya, Kadiam C. Venkata Subbaiah, Feng Jiang…·Peng Yao

The paper identifies dsRNA structures in uORFs that regulate translation and shows ASO targeting can modulate mORF translation and reduce cardiac hypertrophy.

40 citationstop 5%

humanmouse

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Molecular BiologyNucleic Acids ResearchPeer-reviewedMay 1, 2023

RNA binding protein PRRC2B mediates translation of specific mRNAs and regulates cell cycle progression

Feng Jiang, Omar M. Hedaya, Eng-Soon Khor…·Peng Yao

This study identifies PRRC2B as an RNA binding protein that regulates translation of specific mRNAs, including cell cycle regulators, and inhibits cell proliferation by affecting G1/S phase transition.

29 citations

humanbulk RNA-seq

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