Molecular BiologyNature CommunicationsPeer-reviewed
Secondary structures that regulate mRNA translation provide insights for ASO-mediated modulation of cardiac hypertrophy
Omar M. Hedaya, Kadiam C. Venkata Subbaiah, Feng Jiang…·Peng Yao
The paper identifies dsRNA structures in uORFs that regulate translation and shows ASO targeting can modulate mORF translation and reduce cardiac hypertrophy.