Author

Jiahong Lu

University of MacauORCID 0000-0002-1147-125XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Han‐Ming SheniD· 2 shared Alexander D. Carlsson· 1 shared Aochu Liu· 1 shared Aston Jiaxi Wu· 1 shared Bingyuan Liu· 1 shared Chunping LiuiD· 1 shared Dade RongiD· 1 shared Enzhe Lou· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

Han‐Ming ShenORCID

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Author profile →

3 papers

Recent·Most cited

Cell BiologybioRxivPreprintJun 19, 2026

ROS Impair Mitophagy via PARylation of PINK1

Liangliang Gao, Heling Wang, Xuxu Zhuang…·Han‐Ming Shen

This study shows that ROS inhibit mitophagy by activating PARP1, which PARylates PINK1 and impairs its function.

DOI 10.64898/2026.06.18.733102

experimental assaycell signaling & trafficking

𝕏 PostBluesky

Cancer BiologybioRxivPreprintNov 2, 2025

The transcriptional regulatory circuit as a driver and therapeutic target in CML blast crisis

Liling Jiang, Enzhe Lou, Jinxin Fang…·Xianping Shi

This study identifies a transcriptional circuit in CML blast crisis that drives disease progression and shows mebendazole can inhibit it, offering a potential therapeutic strategy.

DOI 10.1101/2025.11.02.686161

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 31, 2025

Senescent astrocytic deposits drive cognitive decline by disrupting tripartite synapse in the aging brain

Er‐Jin Wang, Ming Chen, Yi‐Ting Wang…·Jiahong Lu

This study identifies Senescent Astrocytic Deposits (SAD) as a mechanism linking astrocyte senescence to synaptic dysfunction and cognitive decline in aging brains.

DOI 10.1101/2025.10.31.685958

𝕏 PostBluesky