Ming Chen

This study identifies Senescent Astrocytic Deposits (SAD) as a mechanism linking astrocyte senescence to synaptic dysfunction and cognitive decline in aging brains.

The paper shows that specific peptides inhibit Aβ aggregation and reduce cognitive impairment in Alzheimer's disease models.

This study identifies key copy number variations and genes associated with longevity in late-onset Alzheimer's disease patients using causality network analysis of multi-omics data.

This study identifies molecular networks and key regulators in Alzheimer’s Disease using integrative genomics and experimental validation.