Author

Cuyler Luck

University of California, San FranciscoORCID 0000-0002-1150-0057Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Kyle A. JacobsiD· 2 shared Ross A. OkimotoiD· 2 shared Christopher D. MacaraigiD· 1 shared Julia RiadiD· 1 shared Rovingaile Kriska PonceiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersCancer Biology

Kyle A. JacobsORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 13, 2025

First Generation Tools for the Modeling of Capicua (CIC) - Family Fusion Oncoprotein-Driven Cancers

Cuyler Luck, Kyle A. Jacobs, Julia Riad…·Ross A. Okimoto

The paper develops synthetic CIC-family fusion oncoproteins to study their distinct transcriptional effects in cancer.

DOI 10.1101/2025.05.13.653825

humanexperimental assay

𝕏 PostBluesky

Cancer BiologyCancer Research CommunicationsPeer-reviewedNov 12, 2024

The Capicua C1 Domain is Required for Full Activity of the CIC::DUX4 Fusion Oncoprotein

Cuyler Luck, Kyle A. Jacobs, Ross A. Okimoto

This study shows that the C1 domain of CIC is required for full activity of the CIC::DUX4 fusion oncoprotein, highlighting the importance of breakpoint location in fusion function.

1 citation

humanexperimental assay

𝕏 PostBluesky