Seyed Hossein Helalat

This study introduces a Sortase-based split-Cas9 system for precise genome editing, demonstrating its feasibility in E. coli and human cells with reduced off-target effects.

This study investigates magnetogenetic tools to regulate T cell activity, finding they enhance activation with antigen stimulation but deactivate cells without it.

This paper develops a sortase A-mediated system in E. coli to site-specifically attach proteins to encapsulin nanocompartments, both internally and externally, without in vitro steps.