Mark D. Shen

SORDINO improves fMRI in awake mice by being silent, sensitive, specific, and resistant to motion artifacts, enabling better brain activity mapping.

The paper identifies 253 autism-associated genes using rare variation from 62,429 individuals and finds pleiotropy across physiological systems and developmental disorders.

This study tracks adaptive functioning in Angelman syndrome using Vineland-3, finding slower growth in deletion subtypes and parallel developmental trajectories across subtypes.

This study examines subcortical brain development in infants with Down syndrome compared to controls from 6 to 12 months, finding reduced volumes and slower growth in most structures.

The paper links early cell cycle gene expression in cortical organoids to interindividual variability in infant brain growth trajectories.