Joseph Piven

The paper identifies 253 autism-associated genes using rare variation from 62,429 individuals and finds pleiotropy across physiological systems and developmental disorders.

Among infant siblings of autistic children, greater trial-to-trial variability in visual P1 latency at 6 and 12 months tracked higher 24-month cognitive and language scores; mean P1 measures did not.

This study examines subcortical brain development in infants with Down syndrome compared to controls from 6 to 12 months, finding reduced volumes and slower growth in most structures.

The paper links early cell cycle gene expression in cortical organoids to interindividual variability in infant brain growth trajectories.

The paper identifies a genetic locus on chr3p21.1 associated with lithium-induced neural progenitor proliferation and links it to bipolar disorder risk through the gene GNL3.

This study identifies genome-wide significant associations near FMR1 with Fragile X Syndrome in males, highlighting the complexity of monogenetic disorders.