BioengineeringScientific ReportsPeer-reviewed
Development of a small-molecule epigenetic regenerative therapy. Subcutaneous administration of alginate formulations with high loads of zebularine and retinoic acid promotes tissue growth, vascularization and innervation and induces extensive epigenetic repatterning
Paulina Słonimska, Jakub Baczyński-Keller, Rafał Płatek…·Paweł Sachadyn
This study develops alginate-based formulations of zebularine and retinoic acid for subcutaneous administration, promoting tissue regeneration and epigenetic changes in mice without adverse effects.
2 citations