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Author

Paweł Sachadyn

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Gdańsk University of TechnologyORCID 0000-0002-5087-844XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2Approach:experimental assay· 2Research Focus:cell type annotation· 1Research Focus:differential expression· 1Research Focus:drug response / drug discovery· 1Organism:human· 1Organism:mouse· 1

Frequent Co-Authors

Paulina SłonimskaiD· 2 sharedAgnieszka MickiewicziD· 1 sharedAndrzej ŁośiD· 1 sharedAnna KosteckaiD· 1 sharedArkadiusz PiotrowskiiD· 1 sharedDavid K. CrossmaniD· 1 sharedEwa Iżycka‐ŚwieszewskaiD· 1 sharedJacek GulczyńskiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr
012024: 1 paper (click to filter)120242025: 1 paper (click to filter)12025

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links
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SachadynPaulina Słonimska · 2 shared papersSłonimska · 2Agnieszka Mickiewicz · 1 shared paperMickiewicz · 1Andrzej Łoś · 1 shared paperŁoś · 1Ewa Iżycka‐Świeszewska · 1 shared paperIżycka‐Świes… · 1Jacek Gulczyński · 1 shared paperGulczyński · 1Anna Kostecka · 1 shared paperKostecka · 1Arkadiusz Piotrowski · 1 shared paperPiotrowski · 1David K. Crossman · 1 shared paperCrossman · 1Jakub Baczyński-Keller · 1 shared paperBaczyński-Ke… · 1Justyna Sawicka · 1 shared paperSawicka · 1
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2 shared papersBioengineering
Paulina SłonimskaORCID

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2 papers

Recent·Most cited

Development of a small-molecule epigenetic regenerative therapy. Subcutaneous administration of alginate formulations with high loads of zebularine and retinoic acid promotes tissue growth, vascularization and innervation and induces extensive epigenetic repatterning

Paulina Słonimska, Jakub Baczyński-Keller, Rafał Płatek, Milena Deptuła, Maria Dzierżyńska, Justyna Sawicka, Oliwia Król, Paweł Sosnowski, Magdalena Koczkowska, Anna Kostecka, David K. Crossman, Michael R. Crowley, Piotr Sass, Ryszard Tomasz Smolenski, Piotr Mariusz Skowron, , Paweł Sachadyn

This study develops alginate-based formulations of zebularine and retinoic acid for subcutaneous administration, promoting tissue regeneration and epigenetic changes in mice without adverse effects.

Scientific Reports · Oct 29, 2025Peer-reviewedBioengineering