Author

Spencer E. Bliven

National Institutes of HealthORCID 0000-0002-1200-1698Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:protein structure· 3 Research Focus:protein structure prediction· 3 Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Research Focus:phylogenetics / evolution· 1 Research Focus:protein design· 1

Frequent Co-Authors

Aleix LafitaiD· 3 shared Guido Capitani· 2 shared Althea Parker· 1 shared Andreas PrlićiD· 1 shared Emiliya PoghosyaniD· 1 shared Gabriella ColluiD· 1 shared Inayathulla MohammediD· 1 shared José M. DuarteiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersBioinformatics

Aleix LafitaORCID

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3 papers

Recent·Most cited

Molecular BiologyJournal of Structural BiologyPeer-reviewedJul 16, 2026

Cryo-EM structure of a single-chain β1-adrenoceptor - AmpC β-lactamase fusion protein

Gabriella Collu, Inayathulla Mohammed, Aleix Lafita…·Roger Benoit

The paper presents the cryo-EM structure of a β1-adrenoceptor-AmpC β-lactamase fusion protein in the inactive state, revealing conformational dynamics and potential for GPCR structure elucidation.

2 citations

protein structureexperimental assay

𝕏 PostBluesky

BioinformaticsPLoS Computational BiologyPeer-reviewedApr 22, 2019

Analyzing the symmetrical arrangement of structural repeats in proteins with CE-Symm

Spencer E. Bliven, Aleix Lafita, Peter W. Rose…·Philip E. Bourne

The paper improves CE-Symm to detect and analyze protein symmetry and repeats, enhancing applications in classification and evolutionary studies.

33 citations

protein structurestatistical model

𝕏 PostBluesky

BioinformaticsPLoS Computational BiologyPeer-reviewedApr 30, 2018

Automated evaluation of quaternary structures from protein crystals

Spencer E. Bliven, Aleix Lafita, Althea Parker…·José M. Duarte

The paper presents a method to assess the quaternary structure of proteins from crystal data by combining interface classification with symmetry and topology analysis, achieving 85% precision on a new dataset.

78 citationstop 4%

protein structurestatistical model

𝕏 PostBluesky