Author

Natalie Barretto

Columbia University Irving Medical CenterORCID 0000-0002-1208-0453Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Hemali P. PhatnaniiD· 3 shared Kristy KangiD· 3 shared Aidan C. DalyiD· 2 shared Benjamin T. FullertoniD· 2 shared Colin SmithiD· 2 shared Joana PetrescuiD· 2 shared Obadele CaseliD· 2 shared Shruti Khiste· 2 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersGenomics

Hemali P. PhatnaniORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintJul 28, 2026

A multi-omics characterization reveals distinct molecular signatures in the human motor cortex and lumbar spinal cord in ALS

Natalie Barretto, Benjamin T. Fullerton, Aidan C. Daly…·Hemali P. Phatnani

This study uses multi-omics data to compare molecular signatures in the motor cortex and lumbar spinal cord of ALS patients, finding distinct alterations in MN and glial functions depending on symptom onset site.

DOI 10.64898/2026.07.24.740361

humanbulk RNA-seq

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Cell BiologybioRxivPreprintFeb 19, 2025

Uncovering the Signatures of Cellular Senescence in the Human Dorsolateral Prefrontal Cortex

Nick Sloan, Jason A. Mares, Aidan C. Daly…·Hemali P. Phatnani

The paper identifies senescent cell signatures in the human dorsolateral prefrontal cortex using spatial transcriptomics and single nucleus RNA sequencing, revealing heterogeneity and cell-type-specific aging patterns.

2 citations

humanspatial transcriptomics

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GenomicsCellsPeer-reviewedJun 5, 2020

Cell-type specific in vitro gene expression profiling of stem-cell derived neural models

James A. Gregory, Emily Hoelzli, Rawan Abdelaal…·Hemali P. Phatnani

The paper extends the RiboTag system for cell-type specific RNA depletion in vitro, showing variable efficiency across replicates.

8 citations

mousehuman

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