Author

Emily Hoelzli

Ginkgo Bioworks, Inc. (United States)ORCID 0000-0001-6159-703XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:multiome· 1

Frequent Co-Authors

Alison GoateiD· 1 shared Alyssa MorrowiD· 1 shared Aniketh Janardhan ReddyiD· 1 shared Ankit GuptaiD· 1 shared Ashley ThornaliD· 1 shared Catherine BraineiD· 1 shared Celeste M M. KarchiD· 1 shared Elise D. FlynniD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Alison GoateORCID

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Author profile →

2 papers

Recent·Most cited

ML-driven design of 3' UTRs for mRNA stability

Alyssa Morrow, Ashley Thornal, Elise D. Flynn, Emily Hoelzli, Meimei Shan, Görkem Garipler, Rory D. Kirchner, Aniketh Janardhan Reddy, Sophia Tabchouri, Ankit Gupta, Jean-Baptiste Michel, Uri Laserson

The paper designs stable mRNA 3' UTRs using machine learning and experimental validation, achieving higher protein production in mouse models.

bioRxiv · Oct 7, 2024 · PreprintSynthetic Biology

Cell-type specific in vitro gene expression profiling of stem-cell derived neural models

James A. Gregory, Emily Hoelzli, Rawan Abdelaal, Catherine Braine, Miguel Cuevas, Madeline Halpern, Natalie Barretto, Nadine Schrode, Güney Akbalık, Kristy Kang, Esther Cheng, Kathryn R. Bowles, Steven Lotz, Susan K. Goderie, Celeste M M. Karch, , Hemali P. Phatnani

The paper extends the RiboTag system for cell-type specific RNA depletion in vitro, showing variable efficiency across replicates.

Cells · Jun 5, 2020Peer-reviewedGenomics