Cancer BiologyScience AdvancesPeer-reviewed
TP53-mutant AML with ribosomal gene loss exhibits impaired protein translation and sensitivity to HSP90 inhibition
Jean-François Spinella, Jalila Chagraoui, Isabel Boivin…·Guy Sauvageau
2 citationstop 2%
Author
Isabel Boivin
Institute for Research in Immunology and CancerORCID 0000-0002-1216-3240Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2021-2026 · peak 1/yrCo-Author Collaboration Network
10 top collaborators · 43 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship3 papers
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- ImmunologyMolecular TherapyPeer-reviewed
CD33 Epitope Editing Unlocks UM171-Expanded Cord Blood Grafts for AML Immunotherapy
Bernhard Lehnertz, Maéva Langouët, Sophie Corneau…·Guy Sauvageau
This study edits the CD33 epitope in cord blood HSPCs to reduce toxicity from CD33-targeted therapies while maintaining anti-leukemic efficacy.
3 citations - Developmental BiologyBloodPeer-reviewed
HLF Expression Defines the Human Hematopoietic Stem Cell State
Bernhard Lehnertz, Jalila Chagraoui, Tara MacRae…·Guy Sauvageau
This study identifies HLF as a specific marker for human hematopoietic stem cells and develops a genomic reporter system to track its expression.
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