Author

Nadine Mayotte

Institute for Research in Immunology and CancerORCID 0000-0003-1739-3106Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Developmental Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Organism:human· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Guy SauvageauiD· 4 shared Isabel BoiviniD· 4 shared Bernhard LehnertziD· 3 shared Jalila ChagraouiiD· 3 shared Jean-François SpinellaiD· 3 shared Sophie CorneauiD· 3 shared Tara MacRaeiD· 3 shared Elisa TomelliniiD· 2 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersCancer Biology

Guy SauvageauORCID

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4 papers

Recent·Most cited

Cancer BiologyScience AdvancesPeer-reviewedMay 15, 2026

TP53-mutant AML with ribosomal gene loss exhibits impaired protein translation and sensitivity to HSP90 inhibition

Jean-François Spinella, Jalila Chagraoui, Isabel Boivin…·Guy Sauvageau

2 citationstop 2%

humanbulk RNA-seq

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ImmunologyMolecular TherapyPeer-reviewedNov 11, 2025

CD33 Epitope Editing Unlocks UM171-Expanded Cord Blood Grafts for AML Immunotherapy

Bernhard Lehnertz, Maéva Langouët, Sophie Corneau…·Guy Sauvageau

This study edits the CD33 epitope in cord blood HSPCs to reduce toxicity from CD33-targeted therapies while maintaining anti-leukemic efficacy.

3 citations

humanbulk RNA-seq

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Developmental BiologyBloodPeer-reviewedSep 9, 2021

HLF Expression Defines the Human Hematopoietic Stem Cell State

Bernhard Lehnertz, Jalila Chagraoui, Tara MacRae…·Guy Sauvageau

This study identifies HLF as a specific marker for human hematopoietic stem cells and develops a genomic reporter system to track its expression.

85 citationstop 2%

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintJan 15, 2019

Genetic Landscape of Electron Transport Chain Complex I Dependency in Acute Myeloid Leukemia

Irène Baccelli, Yves Gareau, Bernhard Lehnertz…·Guy Sauvageau

The paper identifies Mubritinib as an ETC1 inhibitor effective against chemotherapy-resistant AML subtypes with OXPHOS hyperactivity and specific mutations.

DOI 10.1101/513887

humanbulk RNA-seq

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