Differential Phagocytosis induces Diverse Macrophage Activation States in Malignant Gliomas
Senthilnath Lakshmanachetty, Kent A. Riemondy, Bridget L. Sanford, Andrew M. Donson, Vincent C. Chen, Ilango Balakrishnan, Eric W. Prince, Todd Cameron Hankinson, Nathan A. Dahl, Rajeev Vibhakar, Nicholas K. Foreman, Sujatha Venkataraman, Siddhartha S. Mitra
This study investigates how differential phagocytosis induced by RT or anti-CD47 therapy affects macrophage activation states in gliomas, showing that combination therapy reduces tumor growth and induces distinct macrophage states.
Journal for ImmunoTherapy of Cancer · Sep 1, 2025Peer-reviewedCancer Biology