Author

Rafael Hospodar Felippe Valverde

Universidade Federal do Rio de JaneiroORCID 0000-0002-1244-814XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Amílcar TanuriiD· 1 shared Carolina da S. G. PedrosaiD· 1 shared Fábio Luís Lima MonteiroiD· 1 shared Letícia R. Q. SouzaiD· 1 shared Luiza M. HigaiD· 1 shared Marcelo Einicker‐LamasiD· 1 shared Stevens Kastrup ReheniD· 1 shared Teresa Puig‐PijuaniD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperNeuroscience

Amílcar TanuriORCID

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1 paper

Recent·Most cited

Copper imbalance linked to oxidative stress and cell death during Zika virus infection in human astrocytes

Teresa Puig‐Pijuan, Letícia R. Q. Souza, Carolina da S. G. Pedrosa, Luiza M. Higa, Fábio Luís Lima Monteiro, Amílcar Tanuri, Rafael Hospodar Felippe Valverde, Marcelo Einicker‐Lamas, Stevens Kastrup Rehen

This study shows that ZIKV infection disrupts copper homeostasis in human astrocytes, leading to oxidative stress and cell death, and that copper chelation can reduce oxidative stress and improve cell viability.

bioRxiv · Dec 29, 2021 · PreprintNeuroscience