Patrick Brest

This study shows glucocorticoids increase P-body numbers and alter mRNA translation fate based on transcript sequence features, not abundance.

The paper maps shared epitopes across human and murine proteins to address immune recognition challenges and provides a web server for epitope detection.

This study identifies USP39 as a critical survival and migration factor in multiple myeloma cells, showing that its disruption leads to ZEB1 degradation and reduced tumor growth.

This study shows GC content influences mRNA decay, storage, and translation in human cells, with AU-rich mRNAs regulated at the translation level and GC-rich mRNAs at the decay level.