Yves Clément

The paper generates a high-quality reference transcriptome for Platynereis dumerilii and analyzes RNA-seq data from posterior regeneration stages to identify gene expression dynamics and key molecular mechanisms.

The paper investigates RNAPIII transcription termination in budding yeast, showing T-tracts are necessary but not sufficient, and secondary structures and Sen1 helicase are important for termination.

This study shows GC content influences mRNA decay, storage, and translation in human cells, with AU-rich mRNAs regulated at the translation level and GC-rich mRNAs at the decay level.

This study constructs enhancer-gene maps for human and zebrafish genomes using evolutionary conservation, revealing correlations between enhancer number and gene expression breadth, and identifying ancestral regulatory relationships.