Author

Patrick B. Walter

University of VictoriaORCID 0000-0002-1254-4086Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Amir SeyfooriiD· 2 shared Mohsen AkbariiD· 2 shared Héctor J. CarunchoiD· 1 shared Julian J. LumiD· 1 shared Kaiwen LiuiD· 1 shared Mahdieh Shokrollahi BaroughiD· 1 shared Meitham AmerehiD· 1 shared Sarah Lane· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Amir SeyfooriORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologyAdvanced SciencePeer-reviewedApr 26, 2025

Metabolic Vulnerabilities of Temozolomide-Resistant Glioblastoma Cells: Implications for Targeted Therapies and Overcoming Chemoresistance

Meitham Amereh, Amir Seyfoori, Shahla Shojaei…·Mohsen Akbari

The paper identifies metabolic vulnerabilities in TMZ-resistant glioblastoma cells, showing that iron reduction enhances the efficacy of TMZ through mechanisms involving Hif1, autophagy, and ROS.

7 citations

humanbulk RNA-seq

BioengineeringAdvanced Healthcare MaterialsPeer-reviewedNov 13, 2024

Tumoroid-on-a-Plate (ToP): Physiologically Relevant Cancer Model Generation and Therapeutic Screening

Amir Seyfoori, Kaiwen Liu, Héctor J. Caruncho…·Mohsen Akbari

This study introduces a 3D tumor model called ToP for generating predictive cancer models and screening therapeutics for glioblastoma and pancreatic adenocarcinoma.

15 citations

humanexperimental assay