Shahla Shojaei

This paper identifies treatment-resilient lipid remodeling in TMZ-resistant glioblastoma cells, showing that resistance is linked to coordinated changes in multiple lipid families rather than single species.

This study shows that autophagy and cholesterol metabolism are remodeled in glioma progression and TMZ resistance, with impaired autophagy linked to reduced cholesterol synthesis and altered lipid profiles.

The paper identifies metabolic vulnerabilities in TMZ-resistant glioblastoma cells, showing that iron reduction enhances the efficacy of TMZ through mechanisms involving Hif1, autophagy, and ROS.

This study identifies BCL2L13 as a regulator of autophagy and ceramide metabolism in glioblastoma, showing distinct effects on metabolic pathways in TMZ-resistant and sensitive cells.

This paper introduces a non-fluorescent immunohistochemistry method to measure autophagy flux, demonstrating its cost-effectiveness and applicability to clinical settings.

This study develops a method to measure autophagy flux in TMZ-resistant glioblastoma cells using imaging and biochemical assays, providing insights into chemoresistance mechanisms.