Author

Ye Che

Pfizer (United States)ORCID 0000-0002-1278-4442Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

Annaliesa S. AndersoniD· 2 shared Huixian WuiD· 2 shared Alexander MuikiD· 1 shared Alexandre Esadze· 1 shared Alexey V. GribenkoiD· 1 shared Andrew P. McKeen· 1 shared Annette B. VogeliD· 1 shared Arthur Illenberger· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

Annaliesa S. AndersonORCID

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2 papers

Recent·Most cited

MicrobiologyPLoS PathogensPeer-reviewedFeb 19, 2025

Structure-Based Design of a Highly Immunogenic, Conformationally Stabilized FimH Antigen for a Urinary Tract Infection Vaccine

Natalie C. Silmon de Monerri, Ye Che, Joshua A. Lees…·Robert G. K. Donald

The paper designs a conformationally stabilized FimH antigen for a UTI vaccine, showing improved immunogenicity and structural similarity to native FimH.

20 citationstop 3%

E. coliprotein structure

𝕏 PostBluesky

ImmunologybioRxivNov 17, 2023

Preclinical Characterization of the Omicron XBB.1.5-Adapted BNT162b2 COVID-19 Vaccine

Kayvon Modjarrad, Ye Che, Wei Chen…·Kena A. Swanson

The monovalent Omicron XBB.1.5-adapted BNT162b2 mRNA vaccine elicits stronger neutralizing antibody responses against XBB.1.5 and related sublineages than the bivalent Wild Type + Omicron BA.4/5 vaccine.

DOI 10.1038/s41541-024-01013-9

mouseexperimental assay

𝕏 PostBluesky