GenomicsbioRxivPreprint
Scalable assessment of genome editing off-targets associated with genetic variants
Jiecong Lin, My Anh Nguyen, Linda Yingqi Lin…·Daniel E. Bauer
The paper develops ABSOLVE-seq to assess genome editing off-targets linked to genetic variants using primary cells and sequencing, enabling evaluation of human genetic diversity's impact on gene editing specificity.
3 citations