Author
Broad InstituteORCID 0000-0003-4081-4351Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Tsai‐Yu Lin, Giacomo Ceoldo, Kimberley D. House…·Danilo Pellin
MELISSA assesses insertional mutagenesis risk by analyzing integration site data, identifying over- and under-targeted genes and their impact on clone fitness.
Jing Zeng, My Anh Nguyen, Pengpeng Liu…·Daniel E. Bauer
This study shows that gene editing of HSCs without ex vivo culture reduces genotoxicity while maintaining therapeutic efficacy for beta-hemoglobinopathy treatment.
Jiecong Lin, My Anh Nguyen, Linda Yingqi Lin…·Daniel E. Bauer
The paper develops ABSOLVE-seq to assess genome editing off-targets linked to genetic variants using primary cells and sequencing, enabling evaluation of human genetic diversity's impact on gene editing specificity.