Cancer BiologybioRxivPreprint
Cell-of-origin shapes tumor subtype in BRCA1-associated triple-negative breast cancer
Tatyana Lev, Angela Lincy Prem Antony Samy, Sharmila Mallya…·Devon A. Lawson
This study identifies two cell-of-origin-driven subtypes of BRCA1-associated TNBC, showing that tumor subtype depends on the cell type initiating the cancer.