Author

Jennifer Lai Yee

University of MichiganORCID 0000-0002-1306-9037Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:variant effect prediction· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:Drosophila· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Jacob Otto KitzmaniD· 2 shared Adham AdamiD· 1 shared Bala Bharathi BurugulaiD· 1 shared Bradley A. WaradyiD· 1 shared Brandon CheniD· 1 shared Cathy SmithiD· 1 shared Claire M. DrysdaleiD· 1 shared Costas Andreas LyssiotisiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersDevelopmental Biology

Jacob Otto KitzmanORCID

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3 papers

Recent·Most cited

A lipid metabolism defect is an underlying contributor to Diamond Blackfan anemia syndrome

Kaiwen Deng, Yu Wang, Joseph C. Min, Xiaofang Liu, Greggory Myers, Lei Yu, Susan Hammoud, Adham Adam, Rilie Saba, Vaneesha Natogi, Claire M. Drysdale, Brandon Chen, Hiroki Ueharu, Jennifer Lai Yee, Jacob Otto Kitzman, , Sharon A Singh

The paper identifies a lipid metabolism defect as a contributor to variable anemia in Diamond Blackfan anemia syndrome using a murine model and transcriptomic analysis.

bioRxiv · May 22, 2025 · PreprintDevelopmental Biology

A Drosophila model to screen Alport syndrome COL4A5 variants for their functional pathogenicity

Jianli Duan, Pei Wen, Yunpo Zhao, Joyce van de Leemput, Jennifer Lai Yee, Damian Fermin, Bradley A. Warady, Susan L. Furth, Derek K. Ng, Matthew Gordon Sampson, Zhe Han

This study uses a Drosophila model to functionally assess COL4A5 variants for pathogenicity in Alport syndrome, identifying four pathogenic variants and three benign ones.

bioRxiv · Mar 6, 2024 · PreprintGenetics

High-throughput splicing assays identify known and novel WT1 exon 9 variants in nephrotic syndrome

Cathy Smith, Bala Bharathi Burugula, Ian Dunn, Swaroop Aradhya, Jacob Otto Kitzman, Jennifer Lai Yee

The paper identifies known and novel splicing-disruptive variants in WT1 exon 9 using high-throughput assays, finding 16 new variants and 19 variants increasing the KTS+/KTS- ratio.

Kidney International Reports · Aug 4, 2023Peer-reviewedGenetic & Genomic Medicine