Joyce van de Leemput

This study identifies cardiac neurons expressing the Akh receptor that mediate high-fat diet-induced arrhythmia in Drosophila.

This paper introduces a Drosophila model to study HIV-1 Nef and APOL1-G1 interaction, showing they synergistically induce ER stress and nephrocyte cell death.

This study shows that a high-fat diet activates the JAK-STAT pathway in Drosophila nephrocytes, leading to structural and functional disruption, and that inhibiting JAK-STAT reverses this dysfunction.

This study uses a Drosophila model to functionally assess COL4A5 variants for pathogenicity in Alport syndrome, identifying four pathogenic variants and three benign ones.

This paper shows that primed human pluripotent stem cells can differentiate to trophoblast stem cells without becoming naive, using specific signaling conditions and revealing a transcriptional network involving BMP5/7 and GATA3.