Mingyang Song

The paper identifies gut bacteria-produced metabolites that inhibit HSD11B2, altering cortisol signaling and linking microbiome activity to blood pressure regulation.

The paper uses deconvolution to identify cell-type-specific DNA methylation and gene expression associations with colorectal cancer risk, finding 178 CpG sites and 68 genes across 26 new loci.

This study improves polygenic risk scores for colorectal cancer by combining Asian and European ancestry data, enhancing risk prediction across diverse racial and ethnic groups.

This study uses Mendelian randomization to show that higher physical activity levels are associated with lower risks of breast and colorectal cancer.