Author

Seraina O. Moser

University of BaselORCID 0000-0002-9722-5956Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:metabolism & bioenergetics· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Alex OdermattiD· 3 shared Denise V. WinteriD· 2 shared A. Sloan DevliniD· 1 shared Alexandra Chassot· 1 shared Ali SassiiD· 1 shared Andrei MoscaluiD· 1 shared Andrew Tan ChaniD· 1 shared Aurélien PommieriD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersPhysiology

Alex OdermattORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintAug 22, 2026

Human Gut Bacteria Convert Endogenous Steroids into Host Cortisol Shuttle Inhibitors

Seraina O. Moser, Jasmine T. Walsh, Philipp M. Späne…·A. Sloan Devlin

The paper identifies gut bacteria-produced metabolites that inhibit HSD11B2, altering cortisol signaling and linking microbiome activity to blood pressure regulation.

DOI 10.64898/2026.08.21.746344

humanmetabolomics

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PhysiologybioRxivPreprintSep 1, 2025

Alterations in glucocorticoid homeostasis following sleeve gastrectomy

Seraina O. Moser, Andrei Moscalu, Cullen F. Roberts…·Alex Odermatt

This study shows that sleeve gastrectomy reduces circulating active/inactive glucocorticoid ratios and improves glucose tolerance in mice by increasing renal HSD11B2 activity.

DOI 10.1101/2025.09.01.673462

mousebulk RNA-seq

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PhysiologybioRxivPreprintJan 9, 2025

Tissular glucocorticoid reactivating enzyme 11beta-HSD1 drives pathogenic myofibroblast differentiation in chronic kidney disease

Grégoire Arnoux, David Legouis, Matthieu Tihy…·Eric Féraille

This study identifies 11beta-HSD1 as a driver of myofibroblast differentiation in CKD, showing its inhibition reduces fibrosis and improves renal function.

1 citation

mousebulk RNA-seq

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